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RECOVERY REVOLUTIONARIES.

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Monday, November 7

Brain scans may show addiction to soda, sugar, and certain processed fatty foods

No comments : Posted by Unknown at 06:00 Labels: and certain processed fatty foods , Brain scans may show addiction to soda , sugar

 

What changes in your brain may be caused by soda, fatty foods, processed foods, and sugar? You can check out the Bloomberg News article by Robert Langreth and Duane D. Stanford, which appeared today in the November 6, Sacramento Bee, "Soda, fatty foods may spur addiction." In that article, studies are reported that show changes in the human brain. But sometimes the average consumer may not know which foods are addictive and which foods are healthier for the individual. Cupcakes may be addictive just like cocaine, according to the article, "Soda, fatty foods may spur addiction." Basically the medical studies at leading universities mentioned in the article show that processed foods and sugary drinks hijack the brain "in ways that resemble addictions to cocaine, nicotine, and other drugs." You have to examine the data, which the article reports is overwhelming. And the point of the article explains that scientists are finding evidence of overlap between drugs in the brain and food. Why does food, well, certain types of food, hit the brain like a bomb or rather like a drug and change the brain in much the same way as addiction to drugs change the brain? Food is medicine, say some scientists. And other researchers say food is addictive. The Lab tests so far have found that sugary drinks and fatty foods may produce addictive behavior in animals. Then human brain scans were done by the scientists. But the scans looked compulsive eaters and obese participants. What the scientists found were disturbances in brain-reward circuits similar to those experienced by drug addicts or drug abusers. In 2011, there are already 28 published studies on food addiction. You can look up these articles in the National Library of Medicine database. See the site, National Library of Medicine - National Institutes of Health. You have on one hand scientists looking at processed, commercial foods that they are calling addictive. But will industry put it's foot in the door so to speak when the food and beverage businesses generate one trillion dollars, according to the article? The news article doesn't state whether the one trillion dollar food industry figure is annual or not. What both the scientists and the industry are watching for is any real proof that fatty foods and snacks sweetened with sugar or corn syrup are addictive. So far, there's no proof in writing with a definitive statement saying certain foods are addictive drugs or behave like addictive drugs in the human brain. On the other hand, for shoppers, the consumer battle depends on what scientists can find that can be proven beyond a reasonable doubt. Now it's a legal problem. You can check out the website of Yale University's Rudd Center for Food Policy and Obesity. See, Rudd Center for Food Policy & Obesity — Home. The site contains numerous articles. See, On Preventing Nutrition Negligence. There also are the results of seminars you can peruse. See, Excess Intake and Taxes on Sugar-Sweetened Beverages: Potential Implications on Healthcare Costs and Selling Public Health Policy in Derivative Markets: Lessons from the 2009-2010 New York State Sugary Beverage Excise Tax Campaigns. For example in the 2011 newsletter of the Rudd Center, you can read a brief article about why the Rudd Center objects to recent criticism of New Jersey Governor Chris Christie, whose suitability as a potential presidential candidate has been challenged because of his body weight. Another focus is the language that health care providers use when discussing a child's weight with parents can reinforce weight-based stigma and jeopardize discussions about health, according to a study recently published by the Rudd Center. The study appeared in the journal Pediatrics. President Obama Urged to Protect Children from Junk-Food Marketing Food advocates across the country are asking the President to act now to protect children from junk-food marketing. The country’s leading researchers and advocates for healthy eating, coordinated by the Prevention Institute, unveiled “We’re Not Buying It,” a video highlighting deceptive marketing to children and launched a campaign urging the President to stand up for children’s health, according to an article posted at the Rudd Center. The Interagency Working Group on Food Marketed to Children (IWG) proposed reasonable, science-based nutrition guidelines to help provide a model for companies that market to kids. However, the food industry and media companies are working to get Congress and the Administration to stop the IWG from finalizing these sensible recommendations. The campaign calls on the President to join parents, doctors, and public health practitioners in standing up for children’s health by supporting the voluntary guidelines, according to the Rudd Center's October 2011 newsletter. Check out the many nutrition-related articles and reports in their current and archived newsletters. Also see the site, EWG Takes a Stand on Food Marketed for Children. Anti-smoking Foods: What foods help motivate people to stop smoking or never start? What area the best foods to motivate you to quit smoking or to never start the habit? First, you avoid some of the most addictive foods, sugar, milk shakes, ice cream, cheese, chocolate, and processed or BBQ'd meats. Instead you eat sweet fruits when you crave sweets, such as an apple or banana. Next, you eat vegetables other than fries. Try a salad of shrimp or salmon, raw spinach, celery, carrots, red bell peppers, yellow squash or zucchini, raw mung bean sprouts, and chopped green onions. What happens to your body when you detox from smoking is a 10-day period of imbalance. The more green and red vegetables and fruits you eat, the quicker you'll get the nicotine toxins out of your body. Also try a little vitamin C, if your health condition permits taking vitamins. Drink lots of filtered, purified water. If milk and cheese causes you to crave suites, avoid dairy products and drink almond milk, hemp milk, or hazelnut milk. Or try a bowl of black rice and raw, organic sauerkraut and a dish of chili beans without meat. By avoiding the four most addictive foods which are sugar, chocolate, cheese, and red meat, especially cheese burgers, you will not stir up cravings for highly addictive foods that most people eat daily without realizing how 'hooked' on sugar, red or cold-cut meat, and cheese they really are. Also, don't load up on bread. Try crackers. Instead eat apples and cinnamon. Spices reduce cravings as do apples. You might cook a pot of boiled brown rice with a handful of raisins or other sweet, dried fruit such as goji berries, blue berries, or cherries and a dash of cinnamon and cloves. When the rice is cooked and fragrant, add a can of coconut milk, and let the cooked rice absorb the coconut milk. Thin the coconut milk with almond milk. Serve chilled. The fragrance of the dried fruit, such as dehydrated nectarines in the brown rice is filling and sweet without addicting you to dairy and table sugar or white rice. If you can't tolerate whole grains, try an egg drop soup made from boiled diced onions, celery and carrots into which you drop by the tablespoonful two beaten eggs. Flavor with cilantro and any spices or seasonings you enjoy. For more bulk, add a cup of cooked chick peas, pinto beans, or black beans to the soup and slices of avocado. Spices cut down on cravings for sweets as well as for other food items familiar to you such as the food that creates cravings which are sugar, cheese, chocolate, and meat. What helps most in food items to help you quit smoking? Apples, ginger, and cinnamon. And adding garlic to any foods also helps you cut the cravings. Think spices and herbs--ginger, cloves, cinnamon, and garlic added to foods. Save the garlic for the savory foods like fish, beans, and grains. Also a dash of curry and turmeric help. The spicier the food as long as you can stand the spices and herbs, the lower the cravings for smoking or for sweets. Sometimes coconut milk because it's medium chain saturated fats also helps you cut the cravings. But go easy on the fats. Olive oil on salads also helps as long as you don't crave lots of cheese with the olive oil. Be aware of your cravings for dairy unless you're lactose intolerant and don't enjoy dairy items such as cheese. Instead, you may prefer organic raw sauerkraut and fermented foods such as tempeh which you could use instead of cheese. For example, try sauerkraut over tempeh, which is fermented soy. Sauerkraut is fermented cabbage. Numerous fermented foods are made more digestible by the fermentation process with cultures, molds, or bacteria that is said to help digestion.

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Sunday, November 6

the Internet has many of us on a very short leash – an addictive one.

No comments : Posted by Unknown at 08:01 Labels: the Internet has many of us on a very short leash – an addictive one.

Whether you’re mid-bite, mid-sentence or perhaps mid-sleep, do you react to that ‘bing’ from your smartphone? Or, is it the flashing red light that gets you?

You’ve programmed your phone to alert you to messages, or has it programmed you to respond?

From the constant smartphone companion to the laptop replacing the lapdog, the Internet has many of us on a very short leash – an addictive one.

The consumer research firm Intersperience surveyed more than 1,000 people in Britain and found quitting the Internet is as hard for some as quitting drinking or smoking.

Without the Internet, 40% said they felt lonely. Ironically, it’s fathomable that 40% of those living with Internet addicts probably feel lonely too.

Laurie Tamblyn, an addictions counsellor in special programs at Toronto’s Bellwood Health Services, says there are many types of Internet addiction, including gambling, gaming, pornography and social networking.

“We’re just beginning to treat this. It is a big problem and it is going to become bigger before people start recognizing that they need to do something about it,” Tamblyn says.

“Some of us believe there is a tsunami coming because we haven’t fully recognized the problem yet.”

Part of that problem is the generation gap. Children today are children of technology – dependent on the social web and its tools.

Addiction is a progressive illness that ends up in isolation, Tamblyn says, so Internet use can be a slippery slope, and can have devastating effects on relationships.

“The amount of time people spend lost in their behaviours is comparable to a drinker spending time at the bar instead of with his family or friends,” Tamblyn says.

“The addiction becomes the focus of the addict’s life. The focus is to interact with the addiction before anything else. If this doesn’t happen, it results in mood swings and irritability.”

Internet addiction can be difficult to diagnose, says Dr. Greg Dubord, who teaches in the psychiatry department at the University of Toronto.

“Drawing the line between normal Internet use and Internet addiction is often difficult, because no set criteria for diagnosing the disorder have been established by the American Psychiatric Association.”

What is easy to recognize, however, is the impact of web overuse on our relationships.

Though social networking allows us to communicate with people all over the world, at times it seems to segregate us more than ever. Real-life interaction is often interrupted by bings and beeps. Thoughts become tweets and e-mails. Our fingers do the walking and the talking now.

From neglecting friends and family members to creating severe relationship problems, the Internet and our attachment to it can consume our lives.

One study documents 396 negative effects of the web on social involvement, including significant family problems, Dubord says.

“Reports have shown that excessive use of the Internet resulted in personal and family problems, with 53% of test-takers reporting severe relationship problems,” he says.

“Personal and family concerns extended to marriages, dating relationships, parent-child relationships, and close friendships.”

Dubord notes one case where a New York woman divorced her husband due to Internet overuse, and an extreme case involving a Korean couple so addicted to virtual games they let their three-month-old daughter starve to death.

If you think you may have a problem, Tamblyn says the best thing to do is ask for help.

“You can get an assessment at any treatment centre, or do it online and it’s anonymous. There are a lot of people struggling, and there’s a lot of help.”

Too e-dependent? Greg Dubord points out some general warning signs:

1. Lose track of time online.

2. Failed attempts at moderating Internet behaviour.

3. Neglecting work, sleep, friends and/or family to spend time online.

4. Turning to the Internet in times of stress or sadness to feel better.

How to cut down, according to Laurie Tamblyn:

1. Give yourself short breaks throughout the day when you can’t check your messages. Try going for a walk without your smartphone.

2. Put your iPad to bed. Set a bedtime for your Internet devices.

3. Wi-Fi-free meals. Wash your hands of wireless devices before eating.

4. Put your computer in a high-traffic area to stay accountable to those around you.

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Saturday, November 5

'I am proud to say that I am a fortunate homosexual man. I am very blessed to be who I am.

No comments : Posted by Unknown at 23:00 Labels: 'I am proud to say that I am a fortunate homosexual man. I am very blessed to be who I am.

The 39-year-old, who is a father to three-year-old twins Matteo and Valentino, has been in a relationship with Carlos for four years.

Ricky Martin is apparently keen to marry Carlos Gonzalez (Getty Images)Ricky Martin is apparently keen to marry Carlos Gonzalez (Getty Images)

He chose to apply for Spanish citizenship in order to take advantage of the country's decision to legalise same sex marriage in 2005, reports El Pais.

The government was seemingly pleased to welcome the Livin' La Vida Loca star and, unusually, did not ask him to renounce his Puerto Rican or US citizenship.

Ricky is yet to comment on the reports, but the newspaper claimed he intended to tie the knot in Spain rather than one of the US states that allows same sex marriage, as he wanted to pay tribute to prime minister Jose Luis Rodriguez Zapatero's support for gay rights.

The singer surprised many of his fans when he came out last year by releasing a statement that read: 'I am proud to say that I am a fortunate homosexual man. I am very blessed to be who I am.'




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Monday, October 31

charity worker employed by one of David Cameron’s Big Society gurus has been arrested on suspicion of smuggling cocaine with a street value of £120,000

No comments : Posted by Unknown at 09:29 Labels: 000 , charity worker employed by one of David Cameron’s Big Society gurus has been arrested on suspicion of smuggling cocaine with a street value of £120

charity worker employed by one of David Cameron’s Big Society gurus has been arrested on suspicion of smuggling cocaine with a street value of £120,000 into Britain.

Former US gang member Derrick ‘Anthony’ Mitchell was held at Heathrow this month after UK Border Agency officers allegedly discovered 3kg of drugs in his luggage. 

Mitchell, 37, is a duty manager at the South London-based Kids Company founded by charity boss Camila Batmanghelidjh. She set it up in 1996 to care for abused, neglected or  abandoned children in London’s inner-city communities. 

She has been described as ‘Britain’s most colourful charity leader’ because of her style, dress sense and selfless approach to charity work. 

The award-winning author and campaigner was invited  to 10 Downing Street last year. 

She also advises former Tory leader Iain Duncan Smith and is thought to be one of the inspirations behind Mr Cameron’s pledge to ‘hug a hoodie’. 
Ms Batmanghelidjh spoke of her shock at the allegations surrounding Mr Mitchell, whom  she described as a ‘street-level youth mentor’.

She said: ‘Obviously, because the judicial process needs to take place, we cannot legally comment. The only thing I can say is that the alleged incident took place while he was on holiday in his own time.

‘At this stage I do not know enough to know the full details. But as a worker, he gave exceptional commitment to the kids over a number of years and I can never take that away from him. 

Pledge: David Cameron's Big Society aims to 'take power away from politicians and give it to people'

Pledge: David Cameron's Big Society aims to 'take power away from politicians and give it to people'

As an organisation, we employ a range of people and a lot of them have had challenging backgrounds as children and we have given them chances. The majority of them go on to do incredibly well.

‘In the situation of this individual, if what is alleged has occurred, he has made an abhorrent choice and I do not agree with it.’ 

Camila Batmanghelidjh said she was shocked at the allegations surrounding Mr Mitchell, claiming he gave 'exceptional commitment to the kids'

Camila Batmanghelidjh said she was shocked at the allegations surrounding Mr Mitchell, claiming he gave 'exceptional commitment to the kids'

Mitchell, of Camberwell, south London, was arrested at Heathrow on October 6 and remanded in custody by Uxbridge magistrates the next day. He will reappear in court in the next month. 

The university undergraduate has previously spoken of deciding to rebuild his life after leaving a violent street gang in Miami.

He claimed he had earlier sold drugs and lost a family member to violence at the age of 19 when his sister bled to death after being stabbed in a leg.

After coming to Britain in his 20s, he began working with the charity about five years ago, attempting to convince youths in gangs to turn their back on crime. 

Kids Company operates from three centres in Southwark, Lambeth and Camden in London, as well as working in 37 inner-city schools.

It employs more than 600 people in full and part-time roles to reach out to 14,000 children from the capital’s most deprived and crime-ridden areas. 

Many of the youngsters live with  parents who are unable to care  for them and have had severely troubled lives.



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Chicago area had the most heroin-related hospital visits in the nation.

No comments : Posted by Unknown at 09:07 Labels: the Chicago area had the most heroin-related hospital visits in the nation.

 

2010 study by Roosevelt University researchers found the Chicago area had the most heroin-related hospital visits in the nation. The drug is cheap, and it's attracting users everywhere including some who are very young. Today's heroin can be snorted or smoked -- not just injected -- and that's led to a change in the typical user. Increasingly, today's addict is young, female and from the suburbs. And the roots of their addiction can be found in their family's medicine cabinet. For many, the road to dependence begins at independence --one of a handful of West Side exits off the Eisenhower serve as the gateway to the nation's busiest heroin corridor. "The ride there you're just anxiety, just, 'Oh I can't wait to get there. I can't wait to get it. I can't wait to feel better,'" said a 19-year-old female heroin addict whose scar are more than skin deep. She grew up far from the west side's rough and tumble streets, amidst the manicured lawns of the far west suburbs which seems an unlikely breeding ground for a new crop of heroin users. "I always thought of them as homeless and not caring about what they look like and real skinny and everything," the 19-year-old addict said. Heroin has never been cheaper and more pure. Just $100 can buy a two day supply. "I knew. The first time I did it I was like, 'This is bad. I like this way too much. And this is going to be bad," said the 19-year-old addict, whose identity ABC7 has hidden. DEA Agent Jack Riley says powerful Mexican drug cartels have partnered with Chicago street gangs to make heroin easily available. "If I had to liken anything to a weapon of mass destruction, it would be heroin," Riley said. After smuggling the drugs here, Riley says the cartels often operate in Spanish-speaking areas near Midway Airport. "They can assimilate into these hard working neighborhoods. They can appear to be great citizens, take care of their lawn, put Christmas lights up," Riley said. The cartels need the gangs to distribute the drugs but officials say fights between the two groups are increasingly to blame for the near-daily violence plaguing some neighborhoods. "What we consider to be senseless violent acts, many of them may be actually connected to the cartel's operations in Chicago," Riley said. It seems the danger is of little deterrent to users. "Within two weeks I was getting sick physically without it, and I needed it," the 19-year-old addict said. It wasn't until an overdose nearly killed her that she began treatment a few weeks ago at New Hope Recovery Center in Geneva. In four years, the facility has seen a seven-fold increase in heroin cases and many involve teens first hooked on prescription painkillers. "They'll run out, and someone will say 'Well, snort some heroin. It'll help you, so you won't go through withdrawals,'" said Jake Epperly, New Hope Recovery Center. That may have been how Billy Roberts began using. The Homer Glen 19-year-old died of an overdose two years ago and his father now warns of heroin's dangers. "I do it for him," said the victim's father John Roberts. "And I'll continue doing it as long as I'm alive. To give my son's life meaning. A former Chicago cop, Roberts says it's time for new solutions. "We need help. The police cannot do this alone. We need a comprehensive, strategic approach to this problem if we're ever going to see these numbers turn downward," Roberts said. To put in perspective how big the problem is here, the Chicago DEA has secured funding for a 90-person strike force to combat the operation run by the cartels and gangs in the city. Officials say it's the only such strike force outside of the U.S.-Mexico border. The 19-year-old woman interviewed by ABC7, who is currently in treatment, says she knows at least 20 other kids her age, from her community, who are current or former users.

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Roxies sell on the street for as much as $30 per pill and offer a high that tops crack, heroin or meth

No comments : Posted by Unknown at 06:50 Labels: heroin or meth , Roxies sell on the street for as much as $30 per pill and offer a high that tops crack
Michael Patrick/news sentinel The two most wanted prescription pills on the streets of East Tennessee. The small pills are Roxie 30 and the large green pill is an Oxycontin 80. The second-generation Oxys, made by Purdue Pharma, are now wrapped in a sticky gelcap coating that will burn nostrils and resists needles.

PHOTO BY MICHAEL PATRICK, COPYRIGHT © 2011 // BUY THIS PHOTO

Michael Patrick/news sentinel The two most wanted prescription pills on the streets of East Tennessee. The small pills are Roxie 30 and the large green pill is an Oxycontin 80. The second-generation Oxys, made by Purdue Pharma, are now wrapped in a sticky gelcap coating that will burn nostrils and resists needles.

Effects of oxycodone: The high caused by oxycodone and other opiates affects nearly every major organ in the human body. So does withdrawal. This chart illustrates some of those effects.

PHOTO BY SOURCE: U.S. DRUG ENFORCEMENT ADMINISTRATION, NATIONAL INSTITUTE ON DRUG ABUSE

Effects of oxycodone: The high caused by oxycodone and other opiates affects nearly every major organ in the human body. So does withdrawal. This chart illustrates some of those effects.

Oxy's out. Roxies rule.A tiny blue pill, no bigger than a baby aspirin, overshadows nearly every other illegal drug on the market in East Tennessee. Men and women beg, haggle, threaten, lie, steal and kill — all for a handful of pills.

"It's the new crack," Knox County Sheriff's Office Lt. John Hopkins said. "Most of the addicts we see don't even shop for Oxys now. They've all switched to Roxies, and it's worse than crack ever was."

Doctors, police and emergency workers see the fallout every day. Sometimes it's a pill-sick addict who steals today to buy tonight's fix. Sometimes it's a baby born shaking with seizures from withdrawal.

Commonly abused prescription drugs

Oxycontin: A time-release form of oxycodone, an opioid painkiller, produced by Purdue Pharma and used to treat chronic pain. Strengths range up to 80 mg per pill. Nicknames include Oxys, O's and hillbilly heroin.

Roxicodone: Instant-release form of oxycodone produced by Xanodyne Pharmaceuticals and used to treat breakthrough pain. Strengths range up to 30 mg per pill. Nicknames include Roxies, blues and stars.

Opana: Time-release form of oxymorphone, a synthetic opioid, produced by Endo Pharmaceuticals. Nicknames include stop signs, biscuits, octagons and Mrs. O.

Methadone: Synthetic opioid, typically prescribed in pill or wafer form, used to treat pain and to ease withdrawal symptoms for opiate addicts.

Percocet, Endocet, Roxicet: Mixtures of oxycodone and acetaminophen.Percodan, Endodan, RoxiprinMixtures of oxycodone and aspirin.

Vicodin, Lortab, Lorcet: Mixtures of hydrocodone and acetaminophen. Nicknames include Vikes and hydros.

Fentanyl: Synthetic opioid, stronger than morphine, typically prescribed in patch or lollipop form. Nicknames include china white and perc-a-pop.

Xanax: Brand name of alprazolam, a benzodiazepine produced by Pfizer and used to treat panic, anxiety and insomnia. Strengths range up to 2 mg. Nicknames include footballs and totem poles.

Valium: Brand name of diazepam, a benzodiazepine produced by Roche and used to treat panic, anxiety and insomnia. Strengths range up to 10 mg.

Klonopin: Brand name of clonazepam, a benzodiazepine produced by Roche and used to treat panic, anxiety and insomnia. Strengths range up to 2 mg.

Ambien: Brand name of zolpidem tartrate, a sedative produced by Sanofi-Aventis. Strengths range up to 10 mg.

Suboxone: Combination of buprenorphine and naloxone, used to treat opiate withdrawal.

Pill Sick: The series

Sunday

Tennessee drug task force waging lonely war on Rx diversion

Law enforcement battling to cut off pain drug pipeline

Drug war's new front makes for unlikely targets

Living for the needle: Addict's life a daily, desperate struggle

Prescription pills are East Tennessee's 'new crack'

A year of pills: Drugs leave trail of damage, crime

Summary findings from the News Sentinel investigation into the pill trade

Sometimes it's a corpse — a dealer killed for pills or an addict who chased the last high off the edge of oblivion.

Oxycodone hydrochloride tablets sell at the pharmacy counter under the brand name Roxicodone and offer quick relief from chronic pain for the old, the aching, the crippled and the dying.

Roxies sell on the street for as much as $30 per pill and offer a high that tops crack, heroin or meth — all without the pesky time-release formula that coats Oxycontin, the drug's sister medication.

"It's the epidemic of the day," Knoxville Police Chief David Rausch said. "Everything is attached to it now. Our investigators will tell you that 90 percent of the folks we see who've committed a crime say it's to get their medicine. That's what they call it — medicine.

"The days of the crack dealer on the corner are slowly waning. It's become the medicine dealer on the street."

Drugs of choice

Three people died last year in South Knox County when two men broke into a former police officer's house to steal legally prescribed painkillers. Police say a North Knoxville man's stepson beat him and his wife to death in August to steal pain pills, then burned down the house to cover up the crime.

A rash of drugstore robberies last fall and winter set a local record. Semiannual drug roundups keep rural jails packed and court dockets clogged.

Officers on the beat report dealing with addicts desperate to avoid jail and the agonies of withdrawal. Sometimes they run. Sometimes they fight.

"We're out here beating the bushes today, and in a few months we'll be out here again doing the same thing," said Capt. David Honeycutt, chief investigator for the Claiborne County Sheriff's Office, as he headed out with a stack of indictments in another drug roundup. "Pills have changed the face of law enforcement. It used to be pot, maybe Valium. Now it's pain pills, and they're crazy as hell on them. You'd be hard-pressed to find a family that's not been hurt by these drugs."

Tennessee topped the nation last year in busts of methamphetamine labs, where addicts churn out toxic waste breaking down cold and sinus pills to produce a homemade stimulant. Meth hasn't gone away, but police say they spend more time and money now fighting to keep the cap on the prescription bottle.

"People are afraid of meth, because everybody doesn't do meth," Newport Police Chief Maurice Shults said. "Everybody doesn't do crack. But everybody's on pills of some kind. Pills come from a doctor. People see that as safe. A doctor gives them out, so they've got to be good."

From Oxy to Roxies

Purdue Pharma's Oxycontin tablets once stood as the gold standard for opiate abusers, with concentrated doses of up to 80 mg of oxycodone locked inside a time-release formula easy to crack. Addicts crushed the pills to powder, then snorted or injected them to turn 12 hours of pain relief into an instant high.

That golden egg gained an extra shell when Purdue introduced a new formula last year meant to cut down on abuse. The second-generation Oxys come wrapped in a sticky gelcap coating that burns nostrils and resists the needle.

Some addicts claim to have found ways to beat the coating. Most don't bother.

Roxicodone and its generic equivalents deliver smaller doses of the same drug to treat the short, sharp bursts of breakthrough pain that plague cancer patients and others between round-the-clock doses of painkillers like Oxy. The pills come in 15 mg and 30 mg strength with no gelcap and no time-release coating, ready to deliver instant relief — or an instant high.

"There's no preparation," said Officer Phil Jinks of the Knoxville Police Department's Repeat Offender Squad. "It's straight out of the bottle."

The easy access and potential for profit have caught on among young and old.

"We're dealing with kids in high school, and we've got people retirement age selling," KCSO Sgt. Chris Bryant said. "Pills are easy to get for kids. We've given several drug education classes to teachers, and the first question is always, 'What are those little blue pills we keep seeing?' Those are Roxies."

Some officials expect the problem will only get worse. Opana, a time-release form of oxymorphone introduced five years ago, and fentanyl, a painkiller 100 times more powerful than morphine, offer a stronger high than the old Oxycontin with an even greater potential for overdosing.

Meanwhile, addicts keep working on ways to crack the new Oxys.

"Any time there's a chemical change, there's somebody out there who can alter the effects of that change," Hamblen County Sheriff Esco Jarnagin said. "I don't think you can stop these people from doing what they're doing. The only thing you can do is try to slow them down."

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Addiction's Brain Abnormalities Can Be Reversed

No comments : Posted by Unknown at 06:38 Labels: Addiction's Brain Abnormalities Can Be Reversed

 

 

Researchers from the University of Minho in Portugal have discovered that rats exposed before birth to glucocorticoids (GC) not only show several brain abnormalities similar to those found in addicts, but become themselves susceptible to addiction (the glucorticoids, which are stress hormones, were used to mimic pre-natal stress).  But even more remarkable, Ana João Rodrigues, Nuno Sousa and colleagues were able to reverse all the abnormalities  (including the addictive behavior) by giving the animals dopamine (a neurotransmitter/ brain chemical).  The study has several implications – for a start it alerts for the dangers of high levels of stress during pregnancy, but - since GC are often prescribed as an anti-inflammatory or to help organ maturation during pregnancy - it also calls for an urgent investigation on the effects of this drug in pregnant women. But it is what we learn about addiction that is most interesting - the work not only unveils stress as a new susceptibility factor for the disease, but  also a very simple treatment that, if translated into humans, could one day mean an effective treatment, and maybe even the prevention of human addiction.  Drug addiction was for a long time a character flaw, a moral problem. Now, instead,  is accepted as the complex brain disease that is with the addict a patient in need of treatment. After all many people try drugs, but only a few become addicts And it is in these few that lays the key to the disease and its treatment. So what do we know about these patients and the disease? First although the psychological and social contexts in which the drug is taken are important,  as much as 50% of the compulsion is in the  individual’s genetic makeup. We know that addiction is linked to the mesolimbic system - the brain area that evolved to provide feelings of pleasure to actions that increase our survival chances, such as eat, sex and social stimulation. In fact, drugs activate the mesolimbic circuit too, only far stronger than any physiologic stimulus.  This leads to the production of very high quantities of dopamine – the brain chemical linked to pleasure – creating the euphoria that brings users back. After while, though, the brain no longer can cope with the constant ” high” and adapts by becoming desensitised to dopamine (produced by any type of stimulus) what leads users to consume more in order to “feel” again and trapping those more susceptible in addiction. And with the brain changes induced by drugs being apparently long-lasting - since both cravings and relapses don’t disappear with time – it is not easy to escape once trapped. Adding another piece to the puzzle, recently the disease was also linked to stress during crucial developmental periods, such as feotal life. In fact, high levels of prenatal stress increase propensity to mental problems and now have been suggested also to substance abuse, with the effects being mediated by glucocorticoids (GC).    Normal 0 false false false EN-GB X-NONE X-NONE MicrosoftInternetExplorer4 Rodrigues and Sousa’s group have a long history of interest in stress and have seen before that  rats from mothers injected with GC while pregnant (mimicking pre-natal stress) show changes in their mesolimbic area and in the dopamine response. So in the study now published, following these results and the addiction-stress link, the researchers investigated the responses to drugs in rats exposed to GC while in the uterus. These rats were found to have a susceptibility to addiction not present in control (non-exposed) rats. When their mesolimbic system was examined they also showed several structural and molecular abnormalities,  including less dopamine. The levels of their dopamine receptor Drd2, despite initially being very high, once they experimented drugs, went to abnormally low levels . So why is this important? Because reduced dopamine and Drd2 levels are typical of addicts suggesting that stress and long-term exposure to drugs affect the brain in very similar ways what could explain why the first could lead to the second.  Normal 0 false false false EN-GB X-NONE X-NONE MicrosoftInternetExplorer4 The good news is that low levels of dopamine can be treated so Rodrigues and colleagues restored the rats’ dopamine levels to normal just to find,much to their surprise, that all the structural and molecular abnormalities induced by prenatal GC were reversed. Even more surprising, the addictive behavior also disappeared. Normal 0 false false false EN-GB X-NONE X-NONE MicrosoftInternetExplorer4 As Ana João Rodrigues explains, “This is a remarkable result because it suggests that with a relatively simple pharmacological approach- restoration of dopamine levels- we can eventually treat, and even more importantly, potentially prevent drug abuse in vulnerable individuals. Of course that we still have a long way to go but our results are quite promising. In fact, if we know where susceptibility to substance abuse lies – and low dopamine and altered Drd2 response seems to be it - then maybe we can find better ways to prevent/treat this disorder. “ Restoring dopamine levels has been used to treat cocaine cravings but the few trials looking at its effect on addiction were never very clear. One possible reason might be the length or the dosages used – in Rodrigues’ study, rats treated for 3 days reverted back to an addictive behavior 3 weeks after the end of the treatment,  but this no longer occurs if the treatment continues for 3 weeks Now it will be necessary to test this new theory in humans what could be problematic with addicts as they are notoriously not the most cooperative or reliable research subjects. Large human studies on the effect of prenatal stress are also difficult to mount but there are a couple of them being run at the moment that could be tagged into such as “Project Ice Storm” in Canada.This study is following women pregnant n January 98 in southern Québec during an extreme ice storm that led to electrical power failures affecting more than 3 million people for as much as 6 weeks during the coldest month of the year(when temperatures can go to -18 C).  It is still early for any studies on addiction(the children are only 13 years old after all) but it will be an interesting place to look, especially since abnormal levels of behavioral and cognitive problems have already been detected by scientists. Drug abuse and addiction carry enormous social and financial costs to society, families and individuals.Only in the US, the National Institute for Drug Abuse calculates that more than600 billion dollars are being spent, annually, to combat the disease. Despite this,a steady increase of drug use among teenagers and in prescription drugs continues with treatments remaining as inefficient as ever.  Rodrigues and Sousa’s work might be the first step towards a solution if their remarkable results can be translated into humans.

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UC Berkeley researchers pinpoint areas of brain linked with addiction

No comments : Posted by Unknown at 06:30 Labels: UC Berkeley researchers pinpoint areas of brain linked with addiction

 

Researchers at UC Berkeley have determined the specific areas of the brain that value and interpret decisions, which they hope may lead to new treatments for individuals who struggle with addiction. By measuring the neural activity of macaque monkeys, researchers were able to pinpoint the two specific ways the brain makes decisions, which they explained in a study published Sunday in the journal Nature Neuroscience. They now understand that neural activity in the brain’s orbitofrontal cortex determines the value of decisions, while neural activity in the anterior cingulate cortex evaluates the difference between expectations and results, which is responsible for future behavior. “The brain is basically a computer, and the neuron is taking information and then giving information that they’ve calculated,” said Jonathan Wallis, associate professor of psychology at UC Berkeley and the principal investigator of the study. “This is the first time we’ve been able to show the specific computation to decision-making in specific areas of the brain. That was really the novelty.” While previous research has determined that these sections of the brain are dysfunctional in addicts, the new research explains how the damage leads to addiction. If these parts of the frontal cortex are impaired, addicts lack the signals that provide them with accurate information about how valuable a choice is, making it less likely that they will learn the consequences of their actions, according to Wallis. “If you’re an addict and this area is impaired, you may not realize your goals, and you potentially are not going to learn from unhealthy decisions,” Wallis said. Wallis and his team conducted the research by testing the neural activity of macaque monkeys as they played games that gauged their ability to make decisions. Researchers could measure the calculations that the monkeys were making in the different areas of the brain, which mimicked the way that humans make decisions. The researchers completed the experiment in 2006 and have spent the last five years analyzing the data. Although still a few steps in the future, the ultimate goal of the study is to use the results to treat for individuals with addictions. “Besides therapy, there is nothing we can do for someone that is severely addicted,” Wallis said. “So far no surgical or pharmaceutical treatments exist. By figuring out what is going on when healthy people are making decisions, we can figure out what is going wrong when addicts make bad decisions and find some ways to target these specific areas of the brain.” While the study has led to a greater understanding of how the brain values decisions, researchers will still need to further investigate how addictive drugs are valued in order to develop more effective treatments, according to Howard Fields, professor of neurology and director of the Wheeler Center for the Neurobiology of Addiction at UC San Francisco. “This is a new and important scientific advance,” Fields said. “It is likely that addiction involves dysfunction of the relation between valuation of outcomes and subsequent decision making. In other words, drugs become overvalued compared to other action outcomes. Only by understanding the relation of valuation to action selection will we fully understand how drugs become addictive. After we do that, we’ll be able to develop more effective treatments.”

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Sunday, October 30

Boy, 17, shot in back in Poplar, east London

No comments : Posted by Unknown at 14:32 Labels: 17 , Boy , east London , shot in back in Poplar

 

teenager has been shot in the back in east London. The 17-year-old boy was wounded in East India Dock Road, Poplar, in the early hours of the morning. A Scotland Yard spokesman said: "A 17-year-old male had a gunshot wound to the back and is in hospital in a serious condition." The attack happened just before 01:00 GMT, police said. Any witnesses to the shooting should call the Metropolitan Police.

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Armed guards are to be deployed on British civilian ships for the first time to protect them from pirates,

No comments : Posted by Unknown at 11:47 Labels: Armed guards are to be deployed on British civilian ships for the first time to protect them from pirates

Armed guards are to be deployed on British civilian ships for the first time to protect them from pirates, David Cameron announced today.

A legal ban on weapon-toting protection staff will be relaxed so that firms can apply for a licence to have them on board in danger zones.

The Prime Minister said radical action was required because the increasing ability of sea-borne Somali criminals to hijack and ransom ships had become 'a complete stain on our world'.

He unveiled the measure after talks at a Commonwealth summit in Australia with leaders of countries in the Horn of Africa over the escalating problem faced in waters off their shores.

Under the plans, the Home Secretary will be given the power to license vessels to carry armed security, including automatic weapons, currently prohibited under firearms laws.

Officials said around 200 ships were expected to be in line to take up the offer, which would only apply for voyages through particular waters in the affected region.

It is expected to be used by commercial firms, rather than private sailors such as hostage victims Paul and Rachel Chandler.

Pirates: There are around 50 ships currently being held hostage

Pirates: There are around 50 ships currently being held hostage

 

Asked if he was comfortable with giving private security operatives the right to 'shoot to kill' if necessary, Mr Cameron told BBC1's Andrew Marr Show: 'We have to make choices.

'Frankly the extent of the hijack and ransom of ships round the Horn of Africa is a complete stain on our world.

'The fact that a bunch of pirates in Somalia are managing to hold to ransom the rest of the world and our trading system is a complete insult and the rest of the world needs to come together with much more vigour.

 

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Drug That Killed Michael Jackson "Was Self-Injected"

No comments : Posted by Unknown at 11:04 Labels: Drug That Killed Michael Jackson

 

The jury hear evidence that MJ had also taken a large number of sleeping pills… 08:42, Sunday, 30 October 2011 The last defence witness in the trial of Dr Conrad Murray, Michael Jackson’s personal physician, has told the courtroom that he believed the star was responsible for his own death.   Dr Paul White told jurors that the most likely cause of death was self-injection of a fatal dose of the anesthetic Propofol, after Murray had already administered a small amount. "With the administration of the additional 25 milligrams that we're speculating was self-injected by Mr Jackson, the level increases rapidly and at the time of death would be almost identical to the level found in the urine at autopsy," Dr White said. He revealed that the superstar also appeared to have taken a large dose of sedatives – eight Lorazepam tablets – earlier in the night without Murray’s knowledge. White said that mixing the two drugs would be deadly. "The combination effect is potentially profound." Earlier this week a specialist testified that Michael may have also been addicted to the painkiller Demerol, and was also a regular user of Botox. Murray is charged with involuntary manslaughter into the star’s untimely death in June 2009. The prosecution has already presented four weeks of evidence so it won’t be long before the jurors retire to decide the verdict. Michael’s sister Janet Jackson recently postponed tour dates in Australia in order to be in LA when the verdict is announced. She explained her decision in a statement: "When I planned these shows, the schedule in California was completely different. After talking with my family last night, I decided we must be together right now.”

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